Climate Change in the High Andes:implications and adaptation strategies for small-scale farmers

Abstract: Global climate change represents a major threat to sustainable farming in the Andes. Farmers have used local ecological knowledge and intricate production systems to cope, adapt and reorganize to meet climate uncertainty and risk, which have always been a fact of life. Those traditional systems are generally highly resilient, but the predicted effects, rates and variability of climate change may push them beyond their range of adaptability. This article examines the extent of actual and potential impacts of climate variability and change on small-scale farmers in the highland Andes of Bolivia, Ecuador and Peru. It describes how climate change impacts agriculture through deglaciation, changes in hydrology, soil and pest and disease populations. The article highlights some promising adaptive strategies currently in use by or possible for producers, rural communities and local institutions to mitigate climate change effects while preserving the livelihoods and environmental and social sustainability of the regio

Potential Impacts of Free Trade Areas and Common Currency on Sustainable Agricultural Export in Africa

Peer reviewedPublisher PD

Strong spin-phonon coupling in infrared and Raman spectra of SrMnO3

Infrared reflectivity spectra of cubic SrMnO3 ceramics reveal 18% stiffening of the lowest-frequency phonon below the antiferromagnetic phase transition occurring at T-N = 233 K. Such a large temperature change of the polar phonon frequency is extraordinary and we attribute it to an exceptionally strong spin-phonon coupling in this material. This is consistent with our prediction from first-principles calculations. Moreover, polar phonons become Raman active below T-N, although their activation is forbidden by symmetry in the Pm (3) over barm space group. This gives evidence that the cubic Pm (3) over barm symmetry is locally broken below T-N due to a strong magnetoelectric coupling. Multiphonon and multimagnon scattering is also observed in Raman spectra. Microwave and THz permittivity is strongly influenced by hopping electronic conductivity, which is caused by small nonstoichiometry of the sample. Thermoelectric measurements show room-temperature concentration of free carriers n(e) = 3.6 x 10(20) cm(-3) and the sample composition Sr2+Mn0.984+Mn0.023+O2.992-. The conductivity exhibits very unusual temperature behavior: THz conductivity increases on cooling, while the static conductivity markedly decreases on cooling. We attribute this to different conductivity of the ceramic grains and grain boundariesclose

Recent advances on smart glycoconjugate vaccines in infections and cancer

Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, no effective vaccines are available for pathogens with a highly variable antigenic load, such as the human immunodeficiency virus or to induce cellular T-cell immunity in the fight against cancer. The recent SARS-CoV-2 outbreak has reinforced the relevance of designing smart therapeutic vaccine modalities to ensure public health. Indeed, academic and private companies have ongoing joint efforts to develop novel vaccine prototypes for this virus. Many pathogens are covered by a dense glycan-coat, which form an attractive target for vaccine development. Moreover, many tumor types are characterized by altered glycosylation profiles that are known as “tumor-associated carbohydrate antigens”. Unfortunately, glycans do not provoke a vigorous immune response and generally serve as T-cell-independent antigens, not eliciting protective immunoglobulin G responses nor inducing immunological memory. A close and continuous crosstalk between glycochemists and glycoimmunologists is essential for the successful development of efficient immune modulators. It is clear that this is a key point for the discovery of novel approaches, which could significantly improve our understanding of the immune system. In this review, we discuss the latest advancements in development of vaccines against glycan epitopes to gain selective immune responses and to provide an overview on the role of different immunogenic constructs in improving glycovaccine efficacy

Environmental movements in space-time: the Czech and Slovak republics from Stalinism to post-socialism

To demonstrate the role of space and time in social movements, the paper analyses the evolution and context of the environmental movement in the Czech and Slovak republics from 1948 to 1998. It shows that the movement's identity was formed under socialism and that political opportunity and resource availability changed markedly over time, as did its organisational and spatial structure. The movement played a significant part in the collapse of the socialist regime, but in the 1990s was marginalised in the interests of building a market economy and an independent Slovakia. Nevertheless a diverse and flexible range of groups existed by the late 1990s. The successive space-times allow analysis of the multiple and changing variables that influence the geography of social movements